AMD Instinct MI250X
The AMD Instinct MI250X is an enterprise supercomputing accelerator based on the CDNA 2 multi-die architecture, famous for powering the world-record Frontier exascale supercomputer. Delivering 128GB of high-bandwidth HBM2e memory with 3.2 TB/s throughput across two primary GPU compute dies connected via 3rd-generation Infinity Fabric, it delivers exceptional double-precision (FP64) performance of up to 47.9 TFLOPS. Operating in an OAM form factor with power consumption up to 560W, it excels in scientific molecular dynamics, climate simulations, and large-scale AI matrix calculations. Secondary market buyers should verify dual-die health in ROCm and inspect OAM socket contacts.
Also written as: AMD Instinct MI250X OAM, MI250X 128GB, Frontier Supercomputer GPU
Specifications
| Brand | AMD |
|---|---|
| Family | Instinct |
| Form factor | OAM (OCP Accelerator Module) |
| Released | Nov 2021 |
| End of sale | Mar 2024 |
| Gpu memory (GB) | 128 |
| Tdp (W) | 560 |
Generations
- Next generation: AMD Instinct MI300X
Reference prices (last 14 days, updated 2026-10-27)
Refurbished: USD 8,500 (1 sighting, Oct 2026)
Used: USD 6,200 (1 sighting, Oct 2026)
All sightings
| Seller | Condition | Price | Note | Seen |
|---|---|---|---|---|
| ebay.com | used | USD 6,200 | Tested pull from HPC cluster, 100% functional | 2026-10-27 |
| serversupply.com | refurbished | USD 8,500 | Refurbished OAM module with 90-day warranty | 2026-10-27 |
Prices seen on public listings on the dates shown, before tax and shipping. Not an offer.
Equivalent models from other brands
Buying a used MI250X: what to check
Inspect OAM contact pads for any signs of pitting or foreign debris, verify that both GCD compute dies report healthy status without thermal throttling, and ensure liquid cooling or high-CFM chassis airflow is available.
FAQ
What architecture powers the MI250X?
The MI250X is built on AMD CDNA 2 architecture, utilizing a dual Graphics Compute Die (GCD) design on a single multi-chip module.
What is the double-precision (FP64) capability of the MI250X?
It delivers up to 47.9 TFLOPS of peak FP64 vector performance and 95.7 TFLOPS of FP64 matrix performance.
What supercomputer famously uses the MI250X?
The Frontier supercomputer at Oak Ridge National Laboratory, the world first verified exascale supercomputer, is powered by MI250X accelerators.
Buying or selling MI250X?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- AMD Instinct MI250X Accelerator Product Brief, checked 2026-10-27