P45641-H24: HPE InfiniBand XDR/Ethernet 2x400GbE 1-port OSFP PCIe6 x16 HHHL CX8 Crypto Adapter
HPE InfiniBand XDR/Ethernet 2x400GbE 1-port OSFP PCIe6 x16 HHHL CX8 Crypto Adapter. Listed by HPE as a network adapter for the ProLiant DL360 Gen12. The pairing comes from the vendor QuickSpecs, which also gives the quantity limits and any controller, firmware or slot requirements. Check those rules and the part number suffix before buying a used unit.
Specifications
| Part number | P45641-H24 |
|---|---|
| Brand | HPE |
| Type | Network adapters |
| Vendor description | HPE InfiniBand XDR/Ethernet 2x400GbE 1-port OSFP PCIe6 x16 HHHL CX8 Crypto Adapter |
Fits these models
Works together
How the HPE P45641-H24 connects to servers, storage and the network: 2 ways, with the hardware on each path.
GPU cluster fabric
InfiniBand adapters and switches must match the generation: HDR is 200Gb, NDR is 400Gb. VPI adapters such as ConnectX-6 and ConnectX-7 can run either InfiniBand or Ethernet.
GPUs
AMD Instinct MI210 PCIe 4.0 dual-slot full-height full-length
AMD Instinct MI300X OAM (OCP Accelerator Module)
NVIDIA Data Center GPU H100 PCIe 80GB PCIe 5.0 dual-slot full-height full-length
NVIDIA Data Center GPU H100 SXM5 80GB SXM5 module
Switches
HPE Aruba CX 9300 1U fixed 400G switch
Arista 7060X 7060DX4-32 1U fixed switch
Arista 7060X6-32D 1U fixed switch
Arista 7280R 7280CR3-32D4 2U fixed switch
iSCSI and NVMe/TCP over Ethernet
Keep the speed the same at all three points: a 25GbE server, a 25GbE switch port and a 25GbE array port. Mixed speeds work but the slowest link sets the pace.
Switches
HPE Aruba CX 8400 8-slot modular chassis- HPE Aruba CX 9300 1U fixed 400G switch
- Arista 7060X 7060DX4-32 1U fixed switch
Arista 7260X 7260CX3-64 2U fixed switch
Optics
MMA1U00-FS NVIDIA Mellanox 400GbE QSFP-DD SR8 Optical Transceiver
MMA4Z00-NS NVIDIA NDR 400Gb/s OSFP Optical Transceiver
Plan and size it
- Draw this setup in the topology planner mrplanb.com
- Tokens per kWh calculator for GPU racks rack-density.com
- Add up rack power and space rack-density.com
- Power, cooling and racks for dense GPU servers mrplanb.com
- HPE SPOCK (HPE storage compatibility) hpe.com
Check compatibility with HPE
Before you buy, confirm the exact configuration against the vendor's own lists: firmware levels, operating systems, adapters and optics that HPE has tested with the HPE P45641-H24.
- Compatibility HPE SPOCK (storage, SAN and host compatibility)
- Part lookup HPE PartSurfer (spare and option part numbers)
- Support HPE Support Center
Buying or selling P45641-H24?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- HPE ProLiant Compute DL360 Gen12 QuickSpecs, checked 2026-10-28