HPE ProLiant ML110 Gen11
The HPE ProLiant ML110 Gen11 is an enhanced single-socket 4.5U tower server engineered to deliver enterprise compute, memory capacity, and storage expansion for small and medium-sized businesses, remote offices, and retail edge deployments. Utilizing a single 4th or 5th Gen Intel Xeon Scalable processor with up to 32 cores, 16 DDR5 memory slots, and PCIe 5.0 expansion, it provides quiet, energy-efficient performance with room to grow without requiring rack infrastructure.
Also written as: ML110 G11, ML110Gen11, ProLiant ML110 Gen 11
Specifications
| Brand | HPE |
|---|---|
| Family | ProLiant ML |
| Form factor | 4.5U tower |
| Released | Mar 2023 |
| Cpu sockets | 1 |
| Cpu platform | Intel Xeon Scalable 4th Gen (Sapphire Rapids) and 5th Gen (Emerald Rapids) Single Socket |
| Memory slots | 16 |
| Memory type | DDR5-4800 / DDR5-5600 SmartMemory RDIMM |
| Memory max (GB) | 4,096 |
| Drive bays | Up to 8 SFF SAS/SATA/NVMe or 8 LFF SAS/SATA |
| Pcie slots | Up to 4 PCIe 5.0 slots plus 1 OCP 3.0 slot |
| Gpu support | Up to 2 single-wide or 1 double-wide PCIe accelerator |
| Network onboard | Embedded 2x 1GbE BCM5720 network adapter plus OCP 3.0 slot; dedicated iLO 6 port |
| Power supply | 500W, 800W, or 1000W Flex Slot hot-plug redundant power supplies |
Generations
- Previous generation: HPE Proliant ML110 Gen10
Reference prices (last 14 days, updated 2026-10-27)
New: USD 2,890 (1 sighting, Oct 2026)
Refurbished: USD 4,200 (1 sighting, Oct 2026)
All sightings
| Seller | Condition | Price | Note | Seen |
|---|---|---|---|---|
| cdw.com | new | USD 2,890 | Base CTO single-socket tower chassis | 2026-10-27 |
| serversupply.com | refurbished | USD 4,200 | 1x Xeon Silver 4410Y, 32GB DDR5, 4LFF | 2026-10-27 |
Prices seen on public listings on the dates shown, before tax and shipping. Not an offer.
Compatible parts
SSDs
- P40499-B21 HPE 1.92TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- P40500-B21 HPE 3.84TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- P63829-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Memory
- P64705-B21 HPE 16GB (1x16GB) Single Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit
- P64706-B21 HPE 32GB (1x32GB) Single Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit
Boot devices
- P48183-B21 HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device
Equivalent models from other brands
- Dell Poweredge T360
- Lenovo Thinksystem ST250 V3
Buying a used ML110 Gen11: what to check
Confirm whether the unit has a redundant power supply cage installed (base configurations often ship with a single non-redundant ATX power supply). Check drive cage configuration (8 SFF vs 4/8 LFF), inspect the condition of the OCP 3.0 card, and verify iLO 6 licensing.
FAQ
Can the ML110 Gen11 support a second CPU?
No. The ML110 Gen11 is strictly a single-socket motherboard design. For dual-socket tower needs, choose the ML350 Gen11.
Does the ML110 Gen11 support DDR5 memory?
Yes. It supports 16 DDR5 RDIMM slots, reaching up to 4TB with 256GB modules.
Can the ML110 Gen11 be rack mounted?
Yes, an optional 4.5U tower-to-rack conversion kit is available.
Buying or selling ML110 Gen11?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- HPE ProLiant ML110 Gen11 Server QuickSpecs, checked 2026-10-27