HPE SimpliVity 325 Gen10 Plus v2
The HPE SimpliVity 325 Gen10 Plus v2 is a modern 1U hyperconverged appliance built on AMD EPYC 7003 series processors and PCIe Gen4 architecture. Delivering elevated compute density and lower total cost of ownership for virtual desktop infrastructure and edge enterprise workloads, it provides high-speed all-flash NVMe and SAS storage options alongside full integration into HPE GreenLake cloud services.
Specifications
| Brand | HPE |
|---|---|
| Family | SimpliVity |
| Form factor | 1U rack |
| Released | Apr 2021 |
| Form factor | 1U rack-mount enclosure |
| Cpu sockets | 1 |
| Cpu support | AMD EPYC 7003 Series (Milan) up to 64 cores |
| Memory slots | 16 |
| Max memory | Up to 2TB DDR4-3200 Registered SmartMemory |
| Pcie standard | PCIe Gen4 expansion slots |
| Storage configuration | All-flash SAS or NVMe enterprise solid-state drives |
| Management | HPE OneView and VMware vCenter Web Client Plugin |
Generations
- Previous generation: HPE SimpliVity 325 Gen10
Works together
How the HPE SimpliVity 325 Gen10 Plus v2 connects to servers, storage and the network: 1 way, with the parts and products on each path.
Hyperconverged cluster
Plan at least two 25GbE ports per node to two switches; all-NVMe clusters often move to 100GbE.
Adapters for the server
P08443-B21 HPE Ethernet 10/25Gb 2-port SFP28 BCM57414 Adapter
P10111-B21 HPE Ethernet 10/25Gb 2-port SFP28 MCX562A-ACAI OCP3 Adapter
P10112-B21 HPE Ethernet 10/25Gb 2-port SFP28 MCX512F-ACHT Adapter
P10115-B21 HPE Ethernet 10/25Gb 2-port SFP28 BCM57414 OCP3 Adapter
Switches
HPE Aruba CX Aruba CX 10000 1U distributed services switch
HPE Aruba CX 8360-32Y4C 1U rack
HPE Aruba CX Aruba CX 9300 1U fixed 400G switch
HPE Aruba CX 8325-48Y8C 1U rack
Optics
QSFP-100G-SR4 Arista 100GBASE-SR4 QSFP28 Optical Transceiver
SFP-10G-SR-AR Arista 10GBASE-SR SFP+ Optical Transceiver
SFP-25G-SR Arista 25GBASE-SR SFP28 Optical Transceiver
Plan and size it
- Draw this setup in the topology planner mrplanb.com
- Add up rack power and space rack-density.com
- Hypervisor advisor: which platform fits you mrplanb.com
- VM platform Ledger: hypervisors scored mrplanb.com
- Virtualization storage Ledger: scored storage platforms mrplanb.com
- HPE SPOCK (HPE storage compatibility) hpe.com
Check compatibility with HPE
Before you buy, confirm the exact configuration against the vendor's own lists: firmware levels, operating systems, adapters and optics that HPE has tested with the HPE SimpliVity 325 Gen10 Plus v2.
- Compatibility HPE SPOCK (storage, SAN and host compatibility)
- Part lookup HPE PartSurfer (spare and option part numbers)
- Support HPE Support Center
Equivalent models from other brands
FAQ
What performance advantage does the v2 offer over the first generation 325?
It introduces AMD EPYC 7003 processors with larger unified L3 caches and PCIe Gen4 bus speeds for higher storage throughput and lower virtualization latency.
Is GreenLake cloud management available for this model?
Yes, the system is fully compatible with HPE GreenLake for Private Cloud and centralized SaaS monitoring.
Buying or selling SimpliVity 325 Gen10 Plus v2?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- HPE SimpliVity 325 Gen10 Plus v2 QuickSpecs (SimpliVity 325 Gen10 Plus v2 QuickSpecs), checked 2026-10-27
- HPE SimpliVity 325 Gen10 Plus v2 Overview and Technical Specifications, checked 2026-10-27