HPE ProLiant XL220n Gen10 Plus Server
The HPE ProLiant XL220n Gen10 Plus is a 1U half-width multi-node server tray designed for the Apollo 2000 Gen10 Plus System. Powered by 3rd Gen Intel Xeon Scalable processors with PCIe Gen4 support and 8-channel DDR4 memory, it delivers extreme compute density for financial services, oil and gas simulations, and web infrastructure.
Specifications
| Brand | HPE |
|---|---|
| Family | ProLiant XL |
| Form factor | 1U half-width tray |
| Released | Apr 2021 |
| Processor | Up to 2 3rd Gen Intel Xeon Scalable processors up to 40 cores and 250W TDP |
| Memory | 16 DDR4 DIMM slots up to 1TB DDR4-3200 MT/s Registered SmartMemory |
| Expansion | PCIe Gen4 x16 low-profile slot and OCP 3.0 mezzanine network slot |
| Storage | Up to 6 SFF SAS/SATA/NVMe drives per tray |
| Management | HPE iLO 5 management with Silicon Root of Trust |
Generations
- Previous generation: HPE ProLiant XL170r Gen10 Server
Compatible parts
Memory
P06039-B21 HPE 256GB (1x256GB) Octal Rank x4 DDR4-3200 CAS-26-22-22 Load Reduced 3DS Smart Memory Kit
OCP adapters
P10118-B21 HPE Ethernet 10/25Gb 2-port SFP28 BCM57414 OCP3 Adapter
SSDs
P50227-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
P64999-B21 HPE 800GB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 SSD
P65007-B21 HPE 1.6TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 SSD
Works together
How the HPE ProLiant XL220n Gen10 Plus Server connects to servers, storage and the network: 4 ways, with the parts and products on each path.
Fibre Channel SAN
Match the speed: 16Gb and 32Gb FC HBAs, switches and array ports work together, and each generation also runs one or two speeds below its own (a 32Gb port runs at 16Gb and 8Gb).
Adapters for the server (check the fit list)
P9D94A HPE StoreFabric SN1200E 16Gb 2-port Fibre Channel Host Bus Adapter
P9M76A HPE StoreFabric SN1600Q 32Gb 2-port Fibre Channel Host Bus Adapter
Q0L13A HPE StoreFabric SN1600E 32Gb 1-port Fibre Channel Host Bus Adapter
Q0L14A HPE StoreFabric SN1600E 32Gb 2-port Fibre Channel Host Bus Adapter
Switches
HPE StoreFabric SN6700B 1U rack
HPE StoreFabric SN3600B 1U rack
HPE StoreFabric SN6600B 1U rack
Brocade G-Series G730 2U
Storage
HPE Alletra 6000 4U rack
HPE Alletra 9000 4U rack mission-critical array
HPE MSA 1060 2U rack entry SAN
HPE MSA 2060 2U rack
HPE MSA 2062 2U rack hybrid SAN
HPE Alletra Storage MP 2U rack
Optics
R0Q20A HPE MSA 16Gb Short Wave Fibre Channel SFP+ 4-pack Transceivers Gen6
C8R24A HPE MSA 16Gb Short Wave Fibre Channel SFP+ 4-pack Transceivers
57-1000262-01 Brocade 16G FC SFP+ ELWL 25 km
iSCSI and NVMe/TCP over Ethernet
Keep the speed the same at all three points: a 25GbE server, a 25GbE switch port and a 25GbE array port. Mixed speeds work but the slowest link sets the pace.
Adapters for the server
- P10118-B21 HPE Ethernet 10/25Gb 2-port SFP28 BCM57414 OCP3 Adapter
Switches
HPE Aruba CX 10000 1U distributed services switch
HPE Aruba CX 8360-32Y4C 1U rack
HPE Aruba CX 9300 1U fixed 400G switch
HPE Aruba CX 8100 1U fixed switch
Storage
- HPE Alletra 6000 4U rack
- HPE Alletra 9000 4U rack mission-critical array
- HPE MSA 1060 2U rack entry SAN
- HPE MSA 2060 2U rack
- HPE MSA 2062 2U rack hybrid SAN
- HPE Alletra Storage MP 2U rack
Optics
R0Q21A HPE MSA 10Gb Short Range iSCSI SFP+ 4-pack Transceivers Gen6
C8R23A HPE MSA 10Gb Short Range iSCSI SFP+ 4-pack Transceivers
QSFP-100G-CWDM4-AR Arista 100GBASE-CWDM4 QSFP28 Optical Transceiver Module
Direct-attached SAS
12Gb SAS uses Mini-SAS HD (SFF-8644) connectors; older 6Gb gear uses Mini-SAS (SFF-8088). Adapter cables exist, but the link runs at the slower speed.
Adapters for the server (check the fit list)
804398-B21 HPE Smart Array E208e-p SR Gen10 12G SAS External Controller
726903-B21 HPE H241 12Gb 2-ports Ext Smart Host Bus Adapter
Storage
- HPE MSA 2060 2U rack
Dell PowerVault ME5012 2U rack
Dell PowerVault ME5024 2U rack
Dell PowerVault ME5084 5U rack
Lenovo ThinkSystem DE6400H 2U rack
Lenovo ThinkSystem DE6600H 2U rack
File storage (NFS and SMB)
Front-end ports face the clients; back-end ports (on scale-out systems) connect the nodes to each other and need their own switch pair.
Adapters for the server
- P10118-B21 HPE Ethernet 10/25Gb 2-port SFP28 BCM57414 OCP3 Adapter
Switches
- HPE Aruba CX 10000 1U distributed services switch
- HPE Aruba CX 8360-32Y4C 1U rack
- HPE Aruba CX 9300 1U fixed 400G switch
- HPE Aruba CX 8100 1U fixed switch
Storage
- HPE Alletra Storage MP 2U rack
Dell PowerScale A300 4U
Dell PowerScale A3000 4U 4-node chassis
Dell PowerScale F900 2U rack
Dell PowerScale H700 4U
Dell PowerScale H7000 4U 4-node chassis
Optics
- R0Q21A HPE MSA 10Gb Short Range iSCSI SFP+ 4-pack Transceivers Gen6
- C8R23A HPE MSA 10Gb Short Range iSCSI SFP+ 4-pack Transceivers
- QSFP-100G-CWDM4-AR Arista 100GBASE-CWDM4 QSFP28 Optical Transceiver Module
Plan and size it
- Draw this setup in the topology planner mrplanb.com
- Add up rack power and space rack-density.com
- Virtualization storage Ledger: scored storage platforms mrplanb.com
- SAN transport and NVMe over FC for backup mrplanb.com
- HPE SPOCK (HPE storage compatibility) hpe.com
Check compatibility with HPE
Before you buy, confirm the exact configuration against the vendor's own lists: firmware levels, operating systems, adapters and optics that HPE has tested with the HPE ProLiant XL220n Gen10 Plus Server.
- Compatibility HPE SPOCK (storage, SAN and host compatibility)
- Part lookup HPE PartSurfer (spare and option part numbers)
- Support HPE Support Center
Equivalent models from other brands
FAQ
What PCIe generation does the XL220n Gen10 Plus support?
It supports PCIe Gen4 interfaces offering double the bandwidth of previous generation buses.
Does the XL220n Gen10 Plus include an OCP 3.0 slot?
Yes, each server tray features a dedicated OCP 3.0 slot for high speed Ethernet networking.
Buying or selling ProLiant XL220n Gen10 Plus Server?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- HPE ProLiant XL220n Gen10 Plus Server QuickSpecs, checked 2026-10-27