Supermicro BigTwin SYS-221BT-HNTR
The Supermicro SYS-221BT-HNTR is a 2U 4-node BigTwin system incorporating 4th and 5th Gen Intel Xeon Scalable processors. Each hot-swap node features two CPUs, 16 DDR5 DIMM slots, six 2.5-inch PCIe 5.0 NVMe drive bays, and an AIOM networking slot, establishing high compute density for enterprise HCI and hyper-scale virtualization.
Specifications
| Brand | Supermicro |
|---|---|
| Family | BigTwin |
| Form factor | 2U 4-node |
| Released | Apr 2023 |
| Form factor | 2U 4-node |
| Sockets | 8 |
| Processor family | Intel Xeon Scalable (4th/5th Gen) |
| Memory slots | 64 |
| Max memory | 16TB DDR5-5600 |
| Drive bays | 24x 2.5-inch hot-swap PCIe 5.0 NVMe (6 per node) |
| Power supplies | 2x 3000W Redundant Titanium |
Generations
- Previous generation: Supermicro BigTwin SYS-220BT-HNTR
Compatible parts
Other parts
AOC-VROCPREMOD Supermicro AOC-VROCPREMOD: Intel VROC Premium, RAID 0, 1, 5, 10
AOC-VROCSTNMOD Supermicro AOC-VROCSTNMOD: Intel VROC Standard, RAID 0, 1, 10
SNK-P3042 Supermicro SNK-P3042: 2x CoolIT Cold Plates for Attachment to CPUs
SNK-P3050-ABT Supermicro SNK-P3050-ABT: 2x Supermicro Cold Plates for Attachment to CPUs
TPM modules
AOM-TPM-9670H-FIPS Supermicro AOM-TPM-9670H-FIPS: SPI Capable TPM 2.0 Provisioned for Server, Horizontal Form Factor, Supporting FIPS 140-2
AOM-TPM-9670H-S Supermicro AOM-TPM-9670H-S: SPI Capable TPM 2.0 Provisioned for Server, Horizontal Form Factor
Drive caddies
MCP-220-00147-0B Supermicro MCP-220-00147-0B: Black gen 3 hot-swap 2.5" Tool-less HDD tray, red tab
MCP-220-00167-0B Supermicro MCP-220-00167-0B: Black gen 8 hot-swap 2.5" Tool-less NVMe tray, orange tab
RAID controllers
SCC-A2NM2241G3-B1 Supermicro SCC-A2NM2241G3-B1: 2x Gen3 Marvell2241 NVMe M.2 RAID with 1x PCIe x16 Gen5, supports only 2x 22x80mm M.2
Works together
How the Supermicro BigTwin SYS-221BT-HNTR connects to servers, storage and the network: 4 ways, with the parts and products on each path.
Fibre Channel SAN
Match the speed: 16Gb and 32Gb FC HBAs, switches and array ports work together, and each generation also runs one or two speeds below its own (a 32Gb port runs at 16Gb and 8Gb).
Switches
Cisco MDS 9396V 2RU
Cisco MDS 9124V 1U rack
Cisco MDS 9148V 1RU
Dell Connectrix DS-7730B 2U switch
Storage
HPE Alletra Storage MP 2U rack
Lenovo ThinkSystem DE6400F 2U rack
Lenovo ThinkSystem DE6400H 2U rack
Lenovo ThinkSystem DE6600F 2U rack
Lenovo ThinkSystem DE6600H 2U rack
Lenovo ThinkSystem DM3010H 2U rack
Optics
57-1000262-01 Brocade 16G FC SFP+ ELWL 25 km
57-1000333-01 Brocade 32G FC SFP+ SWL
57-1000487-01 Brocade 16G FC SFP+ SWL
iSCSI and NVMe/TCP over Ethernet
Keep the speed the same at all three points: a 25GbE server, a 25GbE switch port and a 25GbE array port. Mixed speeds work but the slowest link sets the pace.
Adapters for the server (check the fit list)
AOC-A100G-B2CM Supermicro AOC-A100G-b2CM: OCP 3.0 AIOM 2x 100GbE QSFP28 PCIe 4.0 x16 Broadcom BCM57508
AOC-A25G-B2S-P Supermicro AOC-A25G-B2S-P: AIOM 2-port 25GbE SFP28, Broadcom BCM57414
AOC-A25G-B2SM Supermicro AOC-A25G-b2SM: OCP 3.0 AIOM 2x 25GbE SFP28 PCIe x8 Intel E810-XXVAM2
AOC-A25G-I2SM Supermicro AOC-A25G-i2SM: OCP 3.0 AIOM 4x 25GbE SFP28 PCIe x8 Intel E810-CAM1
Switches
Arista 7060X6-32D 1U fixed switch
Dell PowerSwitch Z9664F-ON 2U switch
HPE Aruba CX 8100 1U fixed switch
Cisco Nexus 9332D-GX2B 1U fixed switch
Storage
- HPE Alletra Storage MP 2U rack
- Lenovo ThinkSystem DE6400H 2U rack
- Lenovo ThinkSystem DE6600H 2U rack
- Lenovo ThinkSystem DM3010H 2U rack
Pure Storage FlashArray //X50 R4 3U rack
Pure Storage FlashArray //X70 R4 3U rack
Optics
QSFP-100G-CWDM4-AR Arista 100GBASE-CWDM4 QSFP28 Optical Transceiver Module
QSFP-100G-LR4-AR Arista 100GBASE-LR4 QSFP28 Optical Transceiver Module
QSFP-100G-SR4 Arista 100GBASE-SR4 QSFP28 Optical Transceiver
Direct-attached SAS
12Gb SAS uses Mini-SAS HD (SFF-8644) connectors; older 6Gb gear uses Mini-SAS (SFF-8088). Adapter cables exist, but the link runs at the slower speed.
Adapters for the server (check the fit list)
AOC-S3008L-L8E Supermicro AOC-S3008L-L8E: Standard LP, 8 internal ports (12Gb/s) Gen-3; HBA
Storage
- Lenovo ThinkSystem DE6400H 2U rack
- Lenovo ThinkSystem DE6600H 2U rack
Dell PowerVault ME5012 2U rack
Dell PowerVault ME5024 2U rack
Dell PowerVault ME5084 5U rack
Lenovo ThinkSystem DE4200H 2U rack
File storage (NFS and SMB)
Front-end ports face the clients; back-end ports (on scale-out systems) connect the nodes to each other and need their own switch pair.
Adapters for the server (check the fit list)
- AOC-A100G-B2CM Supermicro AOC-A100G-b2CM: OCP 3.0 AIOM 2x 100GbE QSFP28 PCIe 4.0 x16 Broadcom BCM57508
- AOC-A25G-B2S-P Supermicro AOC-A25G-B2S-P: AIOM 2-port 25GbE SFP28, Broadcom BCM57414
- AOC-A25G-B2SM Supermicro AOC-A25G-b2SM: OCP 3.0 AIOM 2x 25GbE SFP28 PCIe x8 Intel E810-XXVAM2
- AOC-A25G-I2SM Supermicro AOC-A25G-i2SM: OCP 3.0 AIOM 4x 25GbE SFP28 PCIe x8 Intel E810-CAM1
Switches
- Arista 7060X6-32D 1U fixed switch
- Dell PowerSwitch Z9664F-ON 2U switch
- HPE Aruba CX 8100 1U fixed switch
- Cisco Nexus 9332D-GX2B 1U fixed switch
Storage
- HPE Alletra Storage MP 2U rack
- Lenovo ThinkSystem DM3010H 2U rack
NetApp AFF C250 2U rack
NetApp FAS Series FAS2820 2U rack
Pure Storage FlashArray //E 3U rack
Lenovo ThinkSystem DG5000 2U rack
Optics
- QSFP-100G-CWDM4-AR Arista 100GBASE-CWDM4 QSFP28 Optical Transceiver Module
- QSFP-100G-LR4-AR Arista 100GBASE-LR4 QSFP28 Optical Transceiver Module
- QSFP-100G-SR4 Arista 100GBASE-SR4 QSFP28 Optical Transceiver
Plan and size it
- Draw this setup in the topology planner mrplanb.com
- Add up rack power and space rack-density.com
- Virtualization storage Ledger: scored storage platforms mrplanb.com
- SAN transport and NVMe over FC for backup mrplanb.com
Check compatibility with Supermicro
Before you buy, confirm the exact configuration against the vendor's own lists: firmware levels, operating systems, adapters and optics that Supermicro has tested with the Supermicro BigTwin SYS-221BT-HNTR.
- Compatibility Supermicro tested memory, drives and add-on cards (per system page)
- Support Supermicro Support
Equivalent models from other brands
- Dell PowerEdge C6620 · compare
- HPE Apollo 2000 Gen10 Plus · compare
- Lenovo ThinkSystem SD530 · compare
FAQ
Does the SYS-221BT-HNTR support PCIe 5.0 NVMe SSDs?
Yes, all six front drive bays per node support native PCIe 5.0 NVMe U.2/U.3 solid-state drives.
What power rating is installed in the 2U chassis?
The system features dual 3000W Titanium-grade redundant power supplies with high-line AC support.
Buying or selling SYS-221BT-HNTR?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- Supermicro SYS-221BT-HNTR Specification, checked 2026-10-28