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665249-B21: HPE Ethernet 10Gb 2-port 560FLR-SFP+ Adapter

HPE 665249-B21 Network adapter
HPENetwork adapters

Also listed as: 669281-001, 665246-001, 82599ES · made by Intel

The HPE Ethernet 10Gb 2-port 560FLR-SFP+ Adapter is a high-performance FlexibleLOM 10GbE network card driven by the Intel 82599ES controller. Installing into the dedicated FlexibleLOM slot on HPE ProLiant Gen9 servers, it provides two 10GbE SFP+ cages supporting optical transceivers and direct-attach copper (DAC) cables for low-latency virtualization networking.

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Specifications

Part number665249-B21
BrandHPE
Made byIntel
TypeNetwork adapters
Other numbers669281-001, 665246-001, 82599ES
Statusend of sale
ControllerIntel 82599ES (Niantic)
Host interfacePCIe 2.0 x8 (FlexibleLOM form factor)
Network ports2x 10GbE SFP+ optical / direct-attach copper ports
Data rate10 Gb/s per port (20 Gb/s aggregate)
FeaturesSR-IOV, VMDq, DPDK support, iSCSI boot, FCoE initialization, Jumbo frames up to 9.5KB

About the 665249-B21

665249-B21 is the HPE Ethernet 10Gb 2-port 560FLR-SFP+ FlexibleLOM network adapter for ProLiant Gen9 servers. Built around the proven Intel 82599ES (Niantic) 10GbE network controller, it delivers dual 10Gb/s throughput with hardware virtualization offloads including SR-IOV, VMDq, and DPDK for high-performance packet processing.

Compatibility

Compatible with all HPE ProLiant Gen9 servers featuring FlexibleLOM slots, including DL380 Gen9, DL360 Gen9, DL560 Gen9, DL580 Gen9, ML350 Gen9, Apollo 4200 Gen9, and SimpliVity 380 Gen9. Fits securely into the mezzanine connector with dual captive retention screws.

How to identify a genuine unit

FlexibleLOM mezzanine form-factor card with two SFP+ optical cages and rear status activity LEDs mounted on the metal chassis faceplate. The main white label indicates option part number 665249-B21, spare part number 669281-001, and assembly part number 665246-001.

Buying used

Inspect the internal pins of both SFP+ optical cages for bent or shorted contacts. Verify that the heat sink is firmly attached to the Intel controller ASIC. Test in a live server to ensure both ports link up at 10.0 Gb/s and transmit frames without packet drops or frame check sequence errors.

Reference prices (last 12 months, updated 2026-10-27)

Used: USD 26 (1 sighting, Oct 2026)

All sightings
SellerConditionPriceNoteSeen
ebay.comusedUSD 26Tested working HPE 560FLR-SFP+ 10GbE Dual Port FlexibleLOM2026-10-27

Prices seen on public listings on the dates shown, before tax and shipping. Not an offer.

Fits these models

Works together

How the HPE 665249-B21 connects to servers, storage and the network: 3 ways, with the hardware on each path.

iSCSI and NVMe/TCP over EthernetFile storage (NFS and SMB)Hyperconverged cluster

iSCSI and NVMe/TCP over Ethernet

Keep the speed the same at all three points: a 25GbE server, a 25GbE switch port and a 25GbE array port. Mixed speeds work but the slowest link sets the pace.

Switches

Storage

Optics

iSCSI and NVMe/TCP over Ethernet: how it fits together

File storage (NFS and SMB)

Front-end ports face the clients; back-end ports (on scale-out systems) connect the nodes to each other and need their own switch pair.

Switches

Storage

Optics

File storage (NFS and SMB): how it fits together

Hyperconverged cluster

Plan at least two 25GbE ports per node to two switches; all-NVMe clusters often move to 100GbE.

HCI nodes

Switches

Optics

Hyperconverged cluster: how it fits together

Plan and size it

Check compatibility with HPE

Before you buy, confirm the exact configuration against the vendor's own lists: firmware levels, operating systems, adapters and optics that HPE has tested with the HPE 665249-B21.

Equivalent part numbers

FAQ

What transceivers are supported by the 560FLR-SFP+ adapter?

It supports HPE 10GbE SFP+ SR (455883-B21), LR optical transceivers, and direct-attach copper DAC cables (0.5m to 7m).

Does the 560FLR-SFP+ support SR-IOV for virtualization?

Yes, the Intel 82599ES controller provides hardware-assisted Single Root I/O Virtualization (SR-IOV) for high-performance virtual machine traffic.

Buying or selling 665249-B21?

New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.

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