Supermicro GPU SuperServer 4U Multi-GPU System
The Supermicro 4U Multi-GPU System family houses up to eight or ten double-width PCIe accelerator cards alongside dual Intel Xeon or AMD EPYC processors. Designed for AI model training, deep learning inference, and high-performance computing, the chassis provides dedicated GPU thermal zones and up to four redundant high-output power supplies.
Specifications
| Brand | Supermicro |
|---|---|
| Family | GPU SuperServer |
| Form factor | 4U rack |
| Released | May 2018 |
| Form factor | 4U rack |
| Sockets | 2 |
| Processor family | Intel Xeon Scalable / AMD EPYC |
| Memory slots | 24 |
| Max memory | 6TB |
| Gpu support | Up to 8x or 10x double-width PCIe GPUs |
| Power supplies | 4x 2000W Redundant Titanium |
Works together
How the Supermicro GPU SuperServer 4U Multi-GPU System connects to servers, storage and the network: 4 ways, with the parts and products on each path.
Fibre Channel SAN
Match the speed: 16Gb and 32Gb FC HBAs, switches and array ports work together, and each generation also runs one or two speeds below its own (a 32Gb port runs at 16Gb and 8Gb).
Switches
Storage
Hitachi Virtual Storage Platform VSP F350 2U rack
Hitachi Virtual Storage Platform VSP F370 2U rack
Hitachi Virtual Storage Platform VSP G350 2U rack
Hitachi Virtual Storage Platform VSP G370 2U rack
Lenovo ThinkSystem DE2000H 2U rack
Lenovo ThinkSystem DE4000F 2U rack
Optics
57-1000262-01 Brocade 16G FC SFP+ ELWL 25 km
57-1000333-01 Brocade 32G FC SFP+ SWL
57-1000487-01 Brocade 16G FC SFP+ SWL
iSCSI and NVMe/TCP over Ethernet
Keep the speed the same at all three points: a 25GbE server, a 25GbE switch port and a 25GbE array port. Mixed speeds work but the slowest link sets the pace.
Adapters for the server (check the fit list)
AOC-A100G-B2CM Supermicro AOC-A100G-b2CM: OCP 3.0 AIOM 2x 100GbE QSFP28 PCIe 4.0 x16 Broadcom BCM57508
AOC-A25G-B2S-P Supermicro AOC-A25G-B2S-P: AIOM 2-port 25GbE SFP28, Broadcom BCM57414
AOC-A25G-B2SM Supermicro AOC-A25G-b2SM: OCP 3.0 AIOM 2x 25GbE SFP28 PCIe x8 Intel E810-XXVAM2
AOC-A25G-I2SM Supermicro AOC-A25G-i2SM: OCP 3.0 AIOM 4x 25GbE SFP28 PCIe x8 Intel E810-CAM1
Switches
Arista 7050X 7050CX3-32S 1U fixed switch
Arista 7050X 7050SX3-48YC8 1U fixed switch
Arista 7050X 7050TX3-48C8 1U fixed switch
Arista 7260X 7260CX3-64 2U fixed switch
Storage
- Lenovo ThinkSystem DE2000H 2U rack
Lenovo ThinkSystem DM7000F 3U rack
Dell Isilon F810 4U 4-node chassis
Dell PowerMax 2000 system bay / standard rack
Dell PowerMax 8000 system bay multi-cabinet
Dell PowerProtect DD3300 2U appliance
Optics
QSFP-100G-CWDM4-AR Arista 100GBASE-CWDM4 QSFP28 Optical Transceiver Module
QSFP-100G-LR4-AR Arista 100GBASE-LR4 QSFP28 Optical Transceiver Module
QSFP-100G-SR4 Arista 100GBASE-SR4 QSFP28 Optical Transceiver
Direct-attached SAS
12Gb SAS uses Mini-SAS HD (SFF-8644) connectors; older 6Gb gear uses Mini-SAS (SFF-8088). Adapter cables exist, but the link runs at the slower speed.
Adapters for the server (check the fit list)
AOC-S3008L-L8E Supermicro AOC-S3008L-L8E: Standard LP, 8 internal ports (12Gb/s) Gen-3; HBA
Storage
Dell PowerEdge MX5016s blade- Lenovo ThinkSystem DE2000H 2U rack
- Lenovo ThinkSystem DE4000F 2U rack
Dell PowerVault ME4012 2U rack
Dell PowerVault ME4024 2U rack
Dell PowerVault ME4084 5U rack
File storage (NFS and SMB)
Front-end ports face the clients; back-end ports (on scale-out systems) connect the nodes to each other and need their own switch pair.
Adapters for the server (check the fit list)
- AOC-A100G-B2CM Supermicro AOC-A100G-b2CM: OCP 3.0 AIOM 2x 100GbE QSFP28 PCIe 4.0 x16 Broadcom BCM57508
- AOC-A25G-B2S-P Supermicro AOC-A25G-B2S-P: AIOM 2-port 25GbE SFP28, Broadcom BCM57414
- AOC-A25G-B2SM Supermicro AOC-A25G-b2SM: OCP 3.0 AIOM 2x 25GbE SFP28 PCIe x8 Intel E810-XXVAM2
- AOC-A25G-I2SM Supermicro AOC-A25G-i2SM: OCP 3.0 AIOM 4x 25GbE SFP28 PCIe x8 Intel E810-CAM1
Switches
- Arista 7050X 7050CX3-32S 1U fixed switch
- Arista 7050X 7050SX3-48YC8 1U fixed switch
- Arista 7050X 7050TX3-48C8 1U fixed switch
- Arista 7260X 7260CX3-64 2U fixed switch
Storage
Lenovo ThinkSystem DM5000F 2U rack- Lenovo ThinkSystem DM7000F 3U rack
- Dell Isilon F810 4U 4-node chassis
Lenovo ThinkSystem DM3000H 2U rack
Lenovo ThinkSystem DM5000H 2U rack
Lenovo ThinkSystem DM7000H 3U rack
Optics
- QSFP-100G-CWDM4-AR Arista 100GBASE-CWDM4 QSFP28 Optical Transceiver Module
- QSFP-100G-LR4-AR Arista 100GBASE-LR4 QSFP28 Optical Transceiver Module
- QSFP-100G-SR4 Arista 100GBASE-SR4 QSFP28 Optical Transceiver
Plan and size it
- Draw this setup in the topology planner mrplanb.com
- Add up rack power and space rack-density.com
- Virtualization storage Ledger: scored storage platforms mrplanb.com
- SAN transport and NVMe over FC for backup mrplanb.com
Check compatibility with Supermicro
Before you buy, confirm the exact configuration against the vendor's own lists: firmware levels, operating systems, adapters and optics that Supermicro has tested with the Supermicro GPU SuperServer 4U Multi-GPU System.
- Compatibility Supermicro tested memory, drives and add-on cards (per system page)
- Support Supermicro Support
Equivalent models from other brands
FAQ
How many double-width PCIe GPUs fit into the 4U chassis?
The 4U multi-GPU chassis supports up to eight double-width PCIe accelerator cards in single-root or dual-root configurations, or up to ten cards in select PCIe switch topologies.
What cooling design is used for the GPU zone?
The chassis incorporates heavy-duty counter-rotating fans creating direct front-to-back airflow across the GPU compartment.
Buying or selling 4U Multi-GPU System?
New, refurbished or used. Tell us the quantity and condition and we connect you with a vetted reseller in your region, usually within one working day.
Sources
- Supermicro 4U Multi-GPU System Specification, checked 2026-10-28